Genetically Engineered Pigs for Organ Donation

The podcast discusses the promising advancements in xenotransplantation, particularly focusing on genetically engineered pigs that could serve as a source for human organ transplants. With the ongoing shortage of human organs for transplant, the idea of creating pigs whose organs are more compatible with human bodies presents a potential solution to the organ crisis. Companies like eGenesis are at the forefront of this technology, utilizing CRISPR technology to modify the pig genome, enhancing organ compatibility by removing retroviruses and altering surface sugars that trigger immune responses. Entrepreneurs in the biotech or healthcare sectors could consider developing platforms that facilitate the research, ethical oversight, and commercialization of xenotransplantation technologies, thereby addressing the urgent need for organ transplants while navigating the complex ethical landscape surrounding animal welfare and genetic engineering.